Differences in LDN Sourcing and Dosage Effectiveness

While we had very noticeable success with a prior prescription of LDN from Skips Pharmacy in Florida, we tried a local pharmacy in Los Altos CA, and had very little success - aside from the change in diplopia. None of the other positive effects that we anticipated materialized.

So I ordered 30 tablets of 50mg Naltrexone from a pharmacy in India so that I could compound my own LDN to dial in the correct dosage. That has proven successful, as the Skips dosage was 3mg and worked, and the Los Altos Pharm dose was 4.5mg and was not working, I am now mixing 50mg crushed tablets into 102cc of liquid carrier (using a liquid vitamin base this second batch around). This gives 17 doses at 6cc each for the batch and provides 2.9mg of Naltrexone per dose.

And with the total cost including $24 shipping at $75 for 30 tablets, we are getting 510 doses for $75.

I don't really care about price, but that is pretty cheap for something that has now in the past couple of weeks given Michele the ability to brush her own teeth every night, even when tired. She is also starting to move and use her left arm again as well as her left hand, and can support her weight on her feet for a couple of minutes now when I lift her to a standing position.

The moral of this story is that you need to not give up when at first the Naltrexone does not succeed, but change the dosing and change pharmacies. I am going to experiment with the next batch to see if we lose LDN efficacy at 4.5mg, or if the source/batch really makes a difference.